Selected Research Reports

(updated 10 January 2007)

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Bozarth, M.A., & Wise, R.A. (1982). Localization of the reward-relevant opiate receptors. In L.S. Harris (Ed.), Problems of drug dependence, 1981 (National Institute on Drug Abuse Research Monograph 41, pp. 158-164). Washington, DC: U.S. Government Printing Office.

Bozarth, M.A. & Wise, R.A. (1983). Dissociation of the rewarding and physical dependence-producing properties of morphine. In L.S. Harris (Ed.), Problems of drug dependence, 1982 (National Institute on Drug Abuse Research Monograph 43, pp. 171-177). Washington, DC: U.S. Government Printing Office.

Bozarth, M.A., & Wise, R.A. (1984). Anatomically distinct opiate receptor fields mediate reward and physical dependence. Science, 244, 516-517.

Bozarth, M.A., & Wise, R.A. (1985). Toxicity associated with long-term intravenous heroin and cocaine self-administration in the rat. Journal of the American Medical Association, 254, 81-83.

Bozarth, M.A. (1986). Neural basis of psychomotor stimulant and opiate reward: Evidence suggesting the involvement of a common dopaminergic system. Behavioural Brain Research, 22, 107-116.

Bozarth, M.A., & Wise, R.A. (1986). Involvement of the ventral tegmental dopamine system in opioid and psychomotor stimulant reinforcement. In L.S. Harris (Ed.), Problems of drug dependence, 1985 (National Institute on Drug Abuse Research Monograph 67, pp. 190-196). Washington, DC: U.S. Government Printing Office.

Bozarth, M.A. (1987). (Ed.). Methods of assessing the reinforcing properties of abused drugs. New York: Springer-Verlag. (658 pp.)

Bozarth, M.A. (1987). Intracranial self-administration procedures for the assessment of drug reinforcement. In M.A. Bozarth (Ed.), Methods of assessing the reinforcing properties of abused drugs (173-187). New York: Springer-Verlag.

Bozarth, M.A. (1987). Conditioned place preference: A parametric analysis using systemic heroin injections. In M.A. Bozarth (Ed.), Methods of assessing the reinforcing properties of abused drugs (241-273). New York: Springer-Verlag.

Bozarth, M.A. (1987). An overview of assessing drug reinforcement. In M.A. Bozarth (ed.), Methods of assessing the reinforcing properties of abused drugs (pp. 635-658). New York: Springer-Verlag.

Bozarth, M.A. (1987). Ventral tegmental reward system. In L. Oreland and J. Engel (eds.), Brain reward systems and abuse (pp. 1-17). New York: Raven Press.

Bozarth, M.A. (1987). Neuroanatomical boundaries of the reward-relevant opiate-receptor field in the ventral tegmental area as mapped by the conditioned place preference method in rats. Brain Research, 414, 77-84.

Wise, R.A., & Bozarth, M.A. (1987). A psychomotor stimulant theory of addiction. Psychological Review, 94, 469-492. [PDF file requiring Adobe Acrobat Reader.]

Bozarth, M.A. (1989). New perspectives on cocaine addiction: Recent findings from animal research. Canadian Journal of Physiology & Pharmacology, 67, 1158-1167.

Bozarth, M.A., Murray, A., & Wise, R.A. (1989). Influence of housing conditions on the acquisition of intravenous heroin and cocaine self-administration in rats. Pharmacology Biochemistry & Behavior, 33, 903-907.

Bozarth, M.A. (1990). Drug addiction as a psychobiological process. In D.M. Warburton (ed.), Addiction controversies (pp. 112-134 + refs). London: Harwood Academic Publishers.

Bozarth, M.A. (1991). The mesolimbic dopamine system as a model brain reward system. In P. Willner and J. Scheel-Krüger (eds.), The mesolimbic dopamine system: From motivation to action (pp. 301-330). London: John Wiley & Sons.

Pudiak, C.M., & Bozarth, M.A. (1993). L-NAME and MK-801 attenuate sensitization to the locomotor-stimulating effect of cocaine. Life Sciences, 53, 1517-1524.

Bozarth, M.A. (1994, December). Theories of drug addiction: The evolution of models and concepts. Invited colloquium presented to the Institute of Pharmacology, University of Göteborg, Sweden. [slides only; no lecture notes]

Bozarth, M.A. (1994). Pleasure systems in the brain. In D.M. Warburton (ed.), Pleasure: The politics and the reality (pp. 5-14 + refs). New York: John Wiley & Sons.

Bozarth, M.A. (1994). Opiate reinforcement processes: Reassembling multiple mechanisms. Addiction,89, 1425-1435.

Bozarth, M.A. (1994). Physical dependence produced by central morphine infusions: An anatomical mapping study. Neuroscience & Biobehavioral Reviews, 18, 373-383.

Bozarth, M.A. (1994). Is nicotine addictive? A re-evaluation of the data. Paper presented to the FDA's Substance Abuse Advisory Committee meeting, 2 August 1994, Silver Springs, MD.

Pudiak, C.M., & Bozarth, M.A. (1994). Cocaine fatalities increased by restraint stress. Life Sciences, 55, PL379-PL382.

Bozarth, M.A., & Pudiak, C.M. (1996). Intravenous nicotine self-administration in laboratory animals: Chasing the enigma. Society for Neuroscience Abstracts, 22, 163.

Pudiak, C.M., & Bozarth, M.A. (1996). Modification of cocaine self-administration by nitric oxide synthesis inhibition: A potential treatment for cocaine addiction? Society for Neuroscience Abstracts, 22, 703.

Bozarth, M.A., Pudiak, C.M., & KuoLee, R. (1997). Self-limiting action of nicotine on brain reward mechanisms. Society for Neuroscience Abstracts, 23, 1843. [Press release from New Orleans' Neuroscience meeting distributed by Society for Neuroscience] [PDF file of complete presentation requiring Adobe Acrobat Reader.]

Pudiak, C.M. (1997). The role of nitric oxide in cocaine reinforcement processes [PDF file of complete dissertation requiring Adobe Acrobat Reader]. Unpublished doctoral dissertation, State University of New York at Buffalo. (abstract only)

Pudiak, C.M., & Bozarth, M.A. (1997). Nitric oxide synthesis inhibition attenuates haloperidol-induced supersensitivity. Journal of Psychiatry & Neuroscience, 22, 61-64. [PDF file requiring Adobe Acrobat Reader.]

Bozarth, M.A., Pudiak, C.M., & KuoLee, R. (1998). Effect of chronic nicotine on brain stimulation reward: I. Effect of daily injections. Behavioural Brain Research, 96, 185-188.

Bozarth, M.A., Pudiak, C.M., & KuoLee, R. (1998). Effect of chronic nicotine on brain stimulation reward: II. An escalating dose regimen. Behavioural Brain Research, 96, 189-194.

Bozarth, M.A., Pudiak, C.M., & KuoLee, R. Predicting addiction liability from brain stimulation reward data: I. A comparison of the acute effects of cocaine, pseudoephedrine, nicotine, and caffeine. (abstract only)

Pudiak, C.M., & Bozarth, M.A. (2002). Nitric oxide synthesis inhibition attenuates intravenous cocaine self-administration in rats. Progress in Neuro-psychopharmacology & Biological Psychiatry, 26, 189-196.